比较广藿香和土藿香挥发油化学成分以及两种藿香的显微特征,建立区别广藿香和土藿香的方法。方法:GC-MS法比较广藿香、土藿香挥发油化学成分;显微鉴定法区别广藿香叶、土藿香叶。结果:广藿香油、土藿香油的主要成分分别为广藿香醇(71.45%)和长叶薄荷酮(37.58%),可分别作为广藿香油、土藿香油的特征性成分,用于广藿香、土藿香的鉴定。广藿香叶腺毛头部多为2细胞,土藿香叶腺毛头部多为单细胞;广藿香叶非腺毛以1~4细胞为主,土藿香叶以1~3细胞为主,差别较明显,可用于鉴别广藿香、土藿香。结论:本法简单可靠,可用于广藿香和土藿香的种类鉴别。

Objective:To compare the chemical components of Herba Pogostemonis and Herba Agastachis rugosae, and develop a new method for the identification of them. Methods: Comparing the chemical components in volatile oil of Herba Pogostemonis and Herba Agastachis rugosae by GC-MS, and identifing leaves of them by micro-characteristics. Results: Patchouli alcohol(71.45% ), the major component of Herba Pogostemonis, was its characteristic constituent and pulegone(37. 58% ) was the major component and characteristic constituent of Herba Agastachis rugosae. Two cells formed the head of glandular hairy in Herba Pogostemonis, while only one formed the head of glandular hairy in Herba Agastachis rugosae. The nonglandular hair was mainly constituted by one to three cells in Herba Pogostemonis, while one to four cells constituted the nonglandular hair in Herba Agastachis rugosae. Conclusion: A simple and dependable identification method has been developed for Herba Pogostemonis and Herba Agastachis rug

目的：分析广藿香挥发油的傅里叶变换红外光谱及所含的化学成分。方法采用傅里叶变换红外光谱法和气相色谱-质谱法测定样品挥发油的指纹图谱和化学成分，用色谱峰面积归一法计算各化学成分的相对百分含量。结果从4批广藿香饮片挥发油中共鉴定出20种化学成分，占挥发油总量的90.6%～96.0%。其中特征成分均为广藿香醇（19.6%～46.2%）、广藿香酮（5.2%～27.5%）、α-愈创木烯（3.8%～6.7%）、δ-愈创木烯（4.8%～8.3%）、α-广藿香烯（3.8%～4.3%）、β-广藿香烯（4.5%～14.8%）、刺蕊草烯（4.1%～5.0%）、β-丁香烯（4.3%～5.0%）等。结论上述方法简单，迅速，准确，可用于市售广藿香的质量控制。

Objective To analyze through infrared spectroscopy the chemical components of the essential oils in processed Pogostemonis Herba. Methods The fingerprints and constituents of the essential oils from 4 samples were analyzed by FTIR and GC-MS. The relative content of each component was determined by area normalization. Results The compounds of 20 kinds were all identified from the volatile oils of 4 samples,which accounted for 92.7%-94.3% of the total volatile oils. The characteristic compounds of the volatile oils are patchouli alcohol (19.6%-46.2%),pogostone (5.2%-27.5%),α-guaiene (3.8%-6.7%),δ-guaiene(4.0%-8.3%), α-patchoulene(3.8%-4.3%),β-patchoulene(4.5%-14.8%),seychellene(4.1%-5.0%),β-caryophyllene(4.2%-5.0%),etc. Conclusion This method is simple, rapid and accurate for the quality control.

目的研究药用植物广藿香内生真菌露湿漆斑菌(Myrothecium roridum)菌丝体的化学成分。方法采用正相硅胶柱层析、C18反相硅胶柱层析、sephadex LH-20凝胶柱层析以及薄层层析等色谱方法进行分离纯化,通过波谱数据分析结合文献对照对化合物结构进行鉴定。结果从广藿香内生真菌露湿漆斑菌菌丝体中分离并鉴定出5个化合物,分别为啤酒甾醇(1)、麦角甾醇-3-O-β-D-吡喃葡萄糖苷(2)、吡咯烷酮(3)、大黄酚(4)、尿嘧啶核苷(5)。结论化合物1~4均为首次从该属真菌中分离得到。

Objective To study on the chemical constituents of the mycelia of an endophytic Myrothecium roridum from Pogostemon cablin. (Blanco) Benth.. Methods The compounds were isolated and purified by various chromatographic methods such as silica gel, reverse phase silica gel, sephadex-LH20, preparative TLC,and so on. Their structures were determined by extensive analysis of their spectroscopic data as well as comparison with literature reports. Results Five compounds were isolated and identified as cerevisterol( 1) , ergosterol-3-O-β-D-glucopyranoside(2),pyrrolidone(3), chrysophanol(4) and uridine(5). Conclusion Compounds 1-4 are isolated from the genus Myrothecium for the first time.

目的改进藿香正气口服液制剂处方中广藿香油、紫苏叶油的添加工艺,得到澄清、质量合格的制剂。方法利用滑石粉的分散吸附作用,提高广藿香油、紫苏叶油的溶解性。将广藿香油、紫苏叶油加入到滑石粉中,充分研匀,加入到藿香正气口服液中充分搅拌,过滤,即得澄清制剂。结果制剂澄清,口感好,质量合格。结论该方法可行,工艺简单而稳定,且生产成本低。

Objective To obtain a clear and qualified oral liquid preparation of Huoxiangzhengqi by improving the addition methods of patchouli oil and perilla leaf oil. Methods Pulvis Talci was used to improve the solubility of patchouli oil and perilla leaf oil. Firstly, the two kinds of oil were mixed with Pulvis Talci and triturated sufficiently. Then, the mixture was mixed with the physic liquor and agitated sufficiently. At last, the clear preparation was obtained after filtration. Results The preparation was clear, well-tasted and qualified. Conclusion The improved method is feasible, simple, stabilized and economical.

目的：建立红外光谱技术，快速鉴别不同产地藿香的方法。方法采用傅里叶变换红外光谱技术和二维相关红外光谱法鉴定石牌广藿香（牌香），高要广藿香（肇香），海南广藿香（南香），湛江广藿香（湛香）等四种药材。结果四种不同产地的广霍香（南香、湛香、牌香、肇香）的一维红外光谱和高分辨的二阶导数谱的结果相一致，确切地佐证了南香药材与其它三个产地药材相比具有明显的差异性，很好地解释了南香属于广藿香伪品的论证。二维红外相关谱表明：肇香在940 cm－1的自动峰最强，而牌香和湛香在947 cm－1为最强峰，两者相差了7个波数。湛香1151 cm－1的自动峰明显强于牌香的自动峰，另外湛香947 cm－1的交叉峰也明显强于牌香的交叉峰。凭借自动峰和交叉峰的强弱既可以作为鉴别相似度较大的牌香和湛香的依据。结论红外光谱、二阶导数谱和二维相关红外光谱等三谱技术可以相互补充，相互佐证，可以鉴别四种广藿香的产地，同时也可以看到肇香与牌香、湛香的品质相近，但不完全相同，品质最差的是南香，即海南产的广藿香。

Objective To establish the infrared spectroscopic technique to identify pogostemon ca-blins from different areas .Methods Fourier transform infrared spectroscopy and two-dimensional infrared correlation spectroscopy analysis were used to identify pogostemon cablins , including Paixiang , Zhaoxiang , Nanxiang and Zhanxiang .Results The results of one-dimensional infrared correlation spectroscopy were consistent with those of second derivative spectroscopy , which indicated that Nanxiang was markedly differ-ent from the other three varieties , leading support to the argument that Nanxiang was a fake pogostemon ca -blin.The result of two-dimensional infrared correlation spectroscopy suggested that the strongest automatic peak of Zhaoxiang was at 940 cm-1 while that of Paixiang and Zhanxiang was strongest at 947 cm-1 .More-over, the auto peak of Zhaoxiang was stronger than that of Paixiang at 1151 cm-1 and the cross peak of Zhaoxiang was stronger than that of Paixiang at 947 cm-1