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双语推荐:脊柱畸形

重度脊柱畸形的定义目前仍存在分歧,过去一般认为脊柱侧凸Cobb’s角〉80°即为重度脊柱侧凸,如果同时合并凸侧Bending像上柔韧性90°~100°,伴或不伴脊柱后凸畸形[2-3]。笔者认为,一味强调畸形角度的大小有失偏颇,而应该全面关注畸形的程度、僵硬度、心肺功能及营养状况、既往治疗史以及伴随的椎管内脊髓病变,将其定义为重度复杂脊柱畸形可能更为恰当。20世纪70、80年代,欧美国家的一些学者开始关注重度脊柱畸形,并发表了一系列相关研究[4-8]。然而,随着对畸形早期治疗的重视,欧美国家的重度脊柱畸形患者逐渐减少。相反,诸如中国等发展中国家,由于经济和医疗体制原因,部分脊柱畸形患者,尤其是早发型脊柱侧凸( early onset scoliosis,EOS )早期未能得到恰当处理,使得目前有一大批重度脊柱畸形患者急需诊治。对于我国脊柱外科医生而言,重度脊柱畸形的处理面临巨大挑战,其在诸多方面尚存不少问题,值得关注。重度脊柱畸形的处理是当前脊柱外科的难点,其围手术期处理、治疗方式的选择以及预后仍存在诸多争议,笔者结合自己有限的临床实践,就相关问题谈谈个人的粗浅看法,以供同道参考。
Severe spinal deformity is not an uncommon condition that often arises from untreated early onset scoliosis in developing countries. Patients most often present with severe clinical and radiographic deformity with poor pulmonary function. Previous literature has identiifed the challenges in the treatment of these patients and the higher risk for complications. An assessment of the preoperative, intraoperative, and postoperative factors leading to an optimal result was warranted. The early evaluation should include a multidisciplinary approach from orthopaedic surgeon, pulmonologist, anesthesiologist, and perhaps neurologist to provide a baseline assessment. Advanced imaging of the spine is useful and important. Current surgical strategies include aggressive anterior and posterior column release and osteotomies, either with a front–back or a posterior-only approach. With the extent of the surgical release and segmental instrumentation, the potential for curve correction is in
脊髓或神经的损伤是脊柱侧凸手术的严重并发症,其后果往往是灾难性的。随着对脊柱畸形矫形和内固定能力的提高,尤其自应用三维内固定装置矫正脊柱侧凸以来,脊柱矫形手术,尤其是重度脊柱畸形矫正手术相关的神经并发症成为脊柱矫形外科医生关注的重点。
Spinal or neurological deifcit is one of the most severe complications in surgical correction of scoliosis, which may lead to catastrophic results. The neurological complications related to correction surgery for scoliosis, especially severe scoliosis, are now becoming the focus of spine surgeons. Since the differences exist in patient distribution, etiology and surgical procedures, the rate of neurological complications reported in previous literatures differs. The etiology of scoliosis has been proven to be a related factor for neurological complications in correction of severe scoliosis, and the patients with non-idiopathic scoliosis would take more risks than idiopathic scoliosis patients. Osteotomy, particularly 3-column osteotomy, is another risk factor for neurological complications. Due to complicated procedures in ocrrection of scoliosis, great attetion should paid to the operation plan. Meanwhile, prevention of neurological complications should be focused on and int
目的:探讨脊柱-骨盆曲线和谐角(curve harmony angle, CHA)在量化矢状面相邻弯曲间相关性的作用,并评估其用于评价脊柱畸形矢状面平衡的可行性。方法收集93名正常志愿者及95例脊柱畸形患者(包括退变性脊柱侧凸、特发性脊柱侧凸及强直性脊柱炎)的影像学资料,测量常见脊柱-骨盆矢状面局部参数和整体参数,并对其进行相关分析。测量脊柱-骨盆曲线和谐角,包括颈胸和谐角(cervical-thoracic angle,CTA)、胸腰和谐角(thoracic-lumbar angle,TLA)和腰骶和谐角(lumbar-sacral angle,LSA),比较正常人及不同畸形患者间CHA的特征性改变。根据Schwab-SRS成人脊柱畸形分型矢状面参数进行分组,比较不同矢状面平衡状态下CHA的改变,以检验CHA评价脊柱畸形矢状面平衡的可行性。结果正常志愿者与各类型脊柱畸形患者常用脊柱骨盆参数呈现典型改变。CHA在不同类型的脊柱畸形中呈特征性改变。与正常组比较,退变性脊柱侧凸组与强直性脊柱炎组均表现CTA与LSA减小、TLA增大,且强直性脊柱炎组变化程度更为显著;特发性侧凸组仅TLA减小,而CTA及LSA与正常组的差异无统计学意义。矢状面代偿平衡组较平衡组有较小的LSA,失衡组较平衡组有较小的CTA与LSA和较大的TLA,CHA能反映各代偿阶段的特征性改变。结论 CHA可用于量化描述矢状面相邻弯曲间的关系。正常人、各类型脊柱畸形、以及不同平衡状态下CHA表现出不同的特点,其用于临床矢状面平衡及畸形矫正效果的评估具有可行性。
Objective To introduce Curve Harmony Angle (CHA)to quantify the relationship between adjacent curves of the spine and pelvis and evaluate sagittal balance in spinal deformities. Methods Radiographic analysis of 93 asymptomatic vol-unteers and 95 patients including Degenerative Scoliosis(DS), Adolescent Idiopathic Scoliosis(AIS)and Ankylosing Spondylitis (AS)was performed by measuring sagittal parameters. Correlation study among parameters was further conducted. Curve Harmony Angles(CHAs)including the following three parameters were measured. Cervical-Thoracic Angle (CTA), Thoracic-Lumbar Angle (TLA) and Lumbar-Sacral Angle (LSA). Comparative study between normal population and different spinal disorders were per-formed in order to describe the characteristic changes of CHAs. Besides, according to Schwab SRS adult deformity classification, comparative study of CHAs in different balance status was performed to test the reliability of CHA on sagittal balance evaluation. Results All subjec

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探讨产前超声二维模式结合实时三维成像的表面模式以及骨骼模式诊断胎儿脊柱畸形的应用价值。方法:对1 500例中孕期受检并诊断为脊柱畸形的病例进行回顾性分析。结果:1 500例中孕期受检胎儿中共检出脊柱畸形胎儿19例,经引产后病理解剖或者X线摄片等方式证实,诊断准确率为100%。结论:产前超声二维模式结合实时三维模式的表面成像以及骨骼成像对于准确、全面诊断胎儿脊柱畸形有着重要的临床价值。
Objective:To explore the value of the diagnosis of fetal spinal deformity by combining prenatal two-dimensional model with real-time three-dimensional imaging of surface model and the skeleton model. Methods:To analyze spinal deformity cases diagnosed in our ultrasound department from January to December in 2012. Results:19 fetal spinal de-formities cases were detected from 1 500 pregnant women,they were all confirmed after induced labor pathology anatomy or X-ray radiography. The accuracy rate was 100%. Conclusions:Prenatal two-dimensional model combined with real-time three-dimensional surface model and the skeleton model for accurate and comprehensive diagnosis of fetal spinal de-formity has important clinical value.

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重度脊柱畸形的治疗一直是脊柱外科面临的挑战,由于该类患者多合并心肺功能障碍,严重畸形又导致脊柱僵硬,使得手术矫形难度大、手术时间长和失血量大,患者围手术期各种并发症发生率明显增加[1]。由于术前牵引不但可以增加脊柱、胸廓和脊柱前方结构的柔韧性,还可以改善患者心肺和消化功能、了解牵引状态下脊髓耐受能力及神经并发症的发生情况,因此越来越多的学者采用牵引技术辅助治疗重度脊柱畸形[2-3]。现就目前临床上应用最多的Halo牵引技术综述如下。
Treatment of severe spinal deformity remains a challenge for spine surgeons. Significant pulmonary dysfunction is frequently present, which makes the procedures more daunting. Current surgical strategies include aggressive anterior and posterior column release and osteotomy, either with a front–back or a posterior-only approach. Satisfactory correction results can be achieved. However, the risk of nerve injuries may be increased due to the rapid and strong correction and graft failure may occur because of the increased stress caused by osteopenia. Therefore, the preoperative Halo traction is recommended in the treatment of severe spinal deformity. Both spinal deformity correction and pulmonary function can be improved, and the Halo traction is a helpful adjuvant in the treatment of severe spinal deformity. In this review, the types of Halo traction used mostly in clinical practice and their beneifts are summarized.
背景:椎体环截是近年来提出较多的脊柱矫形概念,因其操作技巧要求高,难度大,并发症多,既往相关文献报道角度各不相同,很多研究者注重并发症分析,究其原因与操作步骤及方式有关。目的:分析单纯后路椎体环截及螺钉置入治疗重度脊柱畸形的疗效和并发症。方法:回顾性分析48例单纯后路椎体环截及螺钉置入治疗重度脊柱畸形患者的临床资料,平均切除椎体1.6个,随访15-64个月,分析所有患者治疗前、治疗后及最后一次随访时Cobb角(冠状面及矢状面),并对手术相关并发症进行分析。结果与结论:纳入的脊柱畸形患者共分5类,其中脊柱侧后凸畸形11例,重度侧凸畸形20例,先天性脊柱畸形4例,球状后凸畸形3例,角状后凸畸形10例。所有患者治疗前平均冠状面畸形角度由84°矫正到35°,总的矫正率达到54%。治疗前平均矢状面畸形角度由90°矫正到42°,矢状面 Cobb 平均减小了48°。手术时间平均545 min(204-1355 min),术中平均估计失血量1610 mL(50-8244 mL),平均失血量达65%。31例治疗后出现并发症,其中13例术中神经功能异常(通过电生理监测及唤醒实验发现),及时处理后患者未出现永久性神经功能障碍。提示单纯后路椎体环截及螺钉置入治疗重度脊柱畸形效果良好,但并发症高,操作难度较大。
BACKGROUND:Vertebral column resection is the frequently mentioned spinal orthopaedic concept. Due to the high requirement of the operation skil , difficulty and more complications, the previous studies have reported from different aspects, and many researchers have focused on the analysis of complications, that may be related with the procedure and manner. OBJECTIVE:To analyze the efficacy and complications of posterior vertebral column resection combined with titanium screw rod fixation for the treatment of severe spinal deformity. METHODS:We retrospectively analyzed 48 patients with severe spinal deformity who treated with posterior vertebral column resection and titanium screw rod fixation, with an average removal of 1.6 vertebral. The patients were fol owed-up for 15-64 months. The Cobb angle (coronal plane and sagittal plane) of the patients before treatment, after treatment and in the final fol ow-up was analyzed, and the relative complications of the surgery were analyzed. RESUL
目的:探讨脊柱后凸畸形的手术方法和治疗体会。方法:应用经椎弓根椎体截骨Gss内固定术治疗脊柱后凸畸形共33例。结果:随访6~28个月,术前Cobb角37°~83°,平均57°,术后Cobb角平均12.5°,平均矫正44.5,°矫正率781.%。结论:经椎弓根椎体截骨结合Gss内固定术是治疗脊柱后凸畸形满意和可靠的方法。
Absrtact Objective:To discuss the operative technique and therapeutic experience in corrction of kyphosis deformity .Method s:There had been 33 cases of kyphosis deformity accepted the treatment of transpedicular vertebral osteotomy and Gss internal fixation .Re sul ts:All cases were followed-up 6 to 28 monthes, the Cobb angle was 37°to 83°before operation with average Cobb angle 57°,after operation the av-erage Cobb angle was 12.5°.The average correction was 44.5°and the correcting rate was 78.1%.Conclusion:Application of transpedicu-lar vertebral osteotomy and Gss internal fixation in correction of kyphosis deformity might be a liable and safe surgical technique .

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目的:探讨脊柱后路手术治疗重度脊柱畸形合并神经功能障碍的疗效。方法回顾性分析14例后路手术治疗重度脊柱畸形合并神经功能障碍患者的临床情况。其中先天性脊柱畸形9例,神经纤维瘤病性脊柱畸形2例,特发性脊柱畸形1例,结核性脊柱畸形1例,退行性脊柱畸形1例。既往有脊柱矫形手术史者2例。术前侧凸Cobb’s角平均98.4°(53~150)°,后凸Cobb’s角平均104°(48~151)°。术前神经功能按Frankel分级,B级2例,C级3例,D级9例。4例行经椎弓根V形截骨术(pediclesubtractionosteotomy, PSO)截骨减压内固定矫形,1例行经后路全脊椎截骨术(posteriorvertebralcolumnresection,PVCR)截骨减压内固定矫形,1例行半椎体切除内固定矫形,4例行椎板切除减压内固定矫形,2例行单纯后路内固定矫形,1例行内固定更换矫形术,1例行内固定取出术。术中7例行体感诱发电位(somatosenory-evokedpotential, SEP)进行神经功能监测,全部患者均行术中唤醒试验。结果14例随访12~69个月,平均36.6个月。术后侧凸Cobb’s角平均55°(5~100)°,矫正率44.1%;后凸Cobb’s角平均62.1°(25~92)°,矫正率40.2%。随访时侧凸和后凸平均丢失1.7°和4.8°。7例术中行SEP监测的患
Objective To evaluate the clinical outcomes of surgical treatment of severe spinal deformity combined with neurological deifcits through a posterior approach. Methods A retrospective study on 14 patients with severe spinal deformity combined with neurological deifcits who were treated by posterior surgery was performed. Etiologic diagnoses were congenital in 9 cases, neurofibromatosis in 2 cases, idiopathic in 1 case, tuberculous in 1 case and degenerative in 1 case. Two patients had prior spinal surgeries. The average preoperative Cobb’s angles of scoliosis and kyphosis were 98.4° ( range:53°-150° ) and 104° ( range:48°-151° ) respectively. According to the Frankel grading system, the preoperative neurological function was rated as grade B in 2 cases, grade C in 3 cases and grade D in 9 cases. Pedicle subtraction osteotomy ( PSO ) was performed on 4 patients, posterior vertebral column resection ( PVCR ) on 1 patient, hemivertebra resection on 1 patient, laminectomy a
脊柱侧弯是指脊柱的一个和多个节段偏离人体中线,向侧方弯曲形成弧度,以致胸廓、骨盆甚至下肢的长度发生变化.该类患者多行脊柱侧弯矫形术,已达到防止畸形进一步发展、矫正畸形,使外观得以改善,生活质量得以提高的目的[1].我院近期收治1例脊柱侧弯矫形术后内固定物取出的患者,此类病例很是少见,其手术配合方面面临很多问题,现报道如下.
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目的 探讨新生儿VACTERL/VATER联合征的临床特征、产前特点、诊断标准及预后,提高对该联合征的认识.方法 报道2例VACTERL/VATER联合征患儿的临床资料,并对近5年来报道的41例新生儿病例进行文献复习.结果 结合文献报道的41例及本研究报道的2例,共43例病例,男女比例为3∶2,性别不明3例,死亡13例.本病联合的几种畸形中,33例存在脊柱畸形,30例存在肛门闭锁,25例存在先天性心脏畸形,25例存在肾脏畸形,23例存在气管食管瘘伴食管闭锁,20例存在肢体畸形.合并的其他畸形中,发生比例最高的为泌尿生殖系统畸形和神经系统畸形.43例病例中以并发3种畸形比例最高,共20例,占46.5%,其中以脊柱畸形、肛门闭锁和肾脏缺陷组合发生比例最高,共4例;其次为4种畸形组合,共16例,占37.2%,以脊柱畸形、肛门闭锁、气管食管瘘和肢体畸形组合发生比例最高,共4例.结论 新生儿VACTERL/VATER联合征是一组非随机的联合畸形,累及多个系统和器官.畸形种类和程度与预后密切相关,产前诊断和多学科干预尤为重要.
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