提本文通过动物实验初步探讨了寒潮天气发生过程中对高血压疾病的影响。在张书余等(2013)研究的基础上,应用TEM1880气象环境模拟箱模拟寒潮温压变化,将27只健康大鼠按每组3个随机分为9组,分别为空白对照组、最低温前3 h组、最低温前1h组、最低温组、最低温后1h组、最低温后3h组、全过程结束组、全过程结束后5h组和全过程结束后7h组,放入模拟箱内,使其受寒潮天气影响,按照寒潮天气过程发生的不同时间先后分批取出实验大鼠,测量各组大鼠的收缩压、心率、体重,并通过腹主动脉采血测量血脂、去甲肾上腺素、血管紧张素Ⅱ及全血粘度等。实验结果分析表明,在寒潮天气发生过程中,冷锋通过后,受冷高压控制,气温迅速下降,当气温达到最低时,全血粘度、去甲肾上腺素和血管紧张素Ⅱ等上升到最大值,致使健康大鼠血压升高,并维持到寒潮天气影响结束以后还不能立刻恢复正常。
Based on Zhang Shuyu’s research (2013),the impact of cold wave on hypertension disease is preliminarily discussed through the animal experiments.The cold wave process is simulated in the environ-mental test chamber (TEM1880).At the same time,27 healthy rats are randomly divided into the control group,3 hours beforeTmin(minimum temperature)group,1 hour beforeTmin group,Tmin group,1 hour af-terTmin group,3 hours afterTmin group,cold wave process group,5 hours after the cold wave process group,7 hours after the cold wave process group,respectively.Each group has 3 rats.All the groups ex-cept the control group are exposed to the cold environment and taken out in accordance with the developing progress of cold wave respectively.The following indexes are measured:systolic blood pressure (SBP), heart rate (HR),weight,blood lipid,noradrenaline (NA),angiotensin Ⅱ (Ang Ⅱ),whole blood viscos-ity (WBV),etc.The experimental results show that the air temperature decreases rapidly under