目的 观察分析地诺前列酮与缩宫素用于足月妊娠引产效果的临床效果和安全性.方法 选取108 例足月妊娠引产产妇,随机分为观察组和对照组,各54 例.分别给予地诺前列酮和缩宫素引产.观察比较两组的引产效果.结果 在宫颈Bishop 评分、12 h 临产率、24 h 临产率、总有效率、阴道分娩率方面比较,观察组明显优于对照组,差异有统计学意义.在不良反应、新生儿结局方面比较,差异无统计学意义.结论 地诺前列酮用于足月妊娠引产效果的临床效果较好,安全性较高,值得推广.

Objective To analyze the efficacy and safety of dinoprostone suppositories and oxytocin for cervical ripening and labor induction in full-term pregnancy. Methods 108 cases of full-term pregnant women who were divided into two groups at random.The two groups were treated with respectively dinoprostone suppositories and oxytocin. The effect of induction of labor were compared between the two groups.Results In the cervical Bishop score,12 hours, 24 hours of labor in labor rate,the total efficiency rate,vaginal delivery rate,the observation group was better than the control group. The difference was statistically significant. The adverse reaction and neonatal outcome comparison had no significant difference.Conclusion Dinoprostone used for induction of term pregnancy is worthy of promotion.

目的探讨宫颈Bishop评分与fFN的测定对预测延/过期妊娠患者引产效果的价值。方法对300例延/过期妊娠患者进行宫颈评分及fFN测定,宫颈评分6分者直接进行催产素引产,≤6分者则给予硫酸普拉睾酮钠促宫颈成熟3d后再次评分及fFN测定并催产素引产,追踪分析宫颈评分及fFN检测结果能否预测孕妇的引产效果。结果随宫颈评分的增加,fFN的阳性率上升,两者之间存在正相关性;当Bishop6且fFN阳性时,引产成功率高达98.8%,Bishop≤6且fFN阴性时,引产成功率为8.8%。结论 fFN对于预测引产成功率的敏感性、特异性、准确率等均要高于宫颈评分,而如果将两者联合进行测量将更明显增加预测的可信度。

Objective To investigate the cervical Bishop score and fFN determination to predict the value of delay/overdue pregnancy induced labor in patients. Methods 300 patients with delayed/overdue pregnancy were tested by the cervical score and fFN determination,the patients with cervical score > 6 points were oxytocin induced labor directly,the patients with six points or lesswere promoted cervical mature by prasterone sulfate sodium three days then tested by cervical bishop score and fFN determination again and oxytocin induced labor,the results were tracked and analyzed weather which could predicting the outcome of induced labor of pregnant women or not. Results With the increase of the cervical score,the positive rate of fFN was rising,there were positive correlations;When the Bishop > 6 and fFN positive,induced labor success rate was as high as 98.8%,Bishop 6 or less and fFN were negative,induced labor success rate was 8.8%. Conclusion fFN for prediction success rate of induced labor in

目的对米非司酮配伍米索前列醇与利凡诺用于中期妊娠引产的效果进行比较和分析。方法选取2011年11月—2013年11月在本院进行引产的中期妊娠孕妇86例,随机分为对照组和观察组各43例,对照组给予利凡诺羊膜腔内注射引产,观察组给予米非司酮和米索前列醇口服引产,比较引产成功率、用药至宫缩时间、用药至胎儿娩出的时间以及宫颈成熟度(Bishop)评分。结果观察组的引产有效率为100.0%,高于对照组90.7%;差异有统计学意义(P0.05)。两组孕妇的宫颈Bishop评分均有升高,但观察组优于对照组,差异有统计学意义(P0.05);两组孕妇出血量比较,差异无统计学意义(P0.05)。结论米非司酮配伍米索前列醇引产应用于中期妊娠引产中具有引产率高、不良反应小、宫颈Bishop评分高、减少清宫率等方面的优势,具有良好的效果。

Objective Effect of mifepristone combined with misoprostol and rivanol in odinopoeia of mid - pregnancy were compared and analyzed. Methods 86 cases of mid - pregnancy in our hospital from November 2011 to November 2013, which were randomly divided into control group and observation group with 43 cases in each group,control group was given intra amniotic injection of rivanol odinopoeia,observation group was given mifepristone combined with misoprostol oral induction,the success rate of odinopoeia,medication to the contraction time,medication to fetuses discharging time and the cervical Bishop score were compared. Results The effective rate of odinopoeia in observation group was 100. 0% ,which was higher than 90. 7% of control group,the difference was statistically significant(P 0. 05). Conclusion Mifepristone combined with misoprostol in odinopoeia of mid - pregnancy has higher induced labor rate,less adverse reaction,higher cervical Bishop score,reducing the rate of curettage and othe

目的：观察米非司酮联合依沙吖啶用于中期妊娠引产的临床效果及安全性。方法：选择孕16~24周要求终止妊娠的健康妇女286例，随机分成两组，观察组采用米非司酮联合依沙吖啶羊膜腔内注射引产，对照组单用依沙吖啶羊膜腔内注射引产，观察两组引产效果及安全性。结果：观察组在总引产时间、宫缩发动时间、宫缩至胎儿娩出时间、产后2小时出血量、胎盘胎膜残留量、宫颈裂伤方面与对照组相比，差异显著(P<0.01)。结论：米非司酮联合依沙吖啶终止中期妊娠能明显缩短引产时间，减少并发症，是一种简单、安全、有效的终止中期妊娠的方法。

Objective:To observe the mifepristone ethacridine trimester abortion for clinical efficacy and safety.Methods:16~24 weeks pregnant to terminate the pregnancy of healthy women 286 cases were randomly divided into two groups,the observation group were treated with mifepristone ethacridine amniotic injection of induction,the control group alone ethacridine amniotic injection of induction were observed induction effect and safety.Results:The total induction time,the contractions start time,the contractions to the time the baby is delivered,two hours post-partum bleeding,residual placental membranes,cervical laceration in the control group,the difference was significant (P<0.01).Conclusion:Mifepristone mid Ethacridine termination of pregnancy can significantly shorten the induction time,reduce complications,is a simple,safe and effective method of second trimester pregnancy termination.

探讨两种浓度缩宫素在孕晚期引产中的应用效果。方法:选择2009年1月~2012年12月在我院计划自然分娩的足月妊娠、有引产指征而无禁忌证的产妇224例,将其随机等分为观察组和对照组。两组均用输液泵调节缩宫素滴速,均从小剂量0.5%开始,观察组最高浓度2%,对照组最高浓度1%,由专人负责、常规调节速度。比较两组引产成功情况及总产程时间。结果:观察组引产成功率高于对照组(P0.05),总产程短于对照组(P0.05)。结论:使用缩宫素引产,由专人负责,严格调节浓度与速度,达到有效子宫收缩是引产成功的关键,能提高引产安全性,缩短引产时间。

Observation the effect and nursing of two different concentrations oxytocin in third trimester abortion .Methods:From January 2009 to December 2012,224 cases of pregnancy in our hospital were randomly divided into observation group and control group .Two groups were used to adjust the speed of infusion pump with small dosage 0.5%.Observation group was the highest concentration of 2%,the control group the highest concentration of 1%. Results:In the observation group,the success rate was higher than the control group,and the production process of the total labor was shorter than the control group (P<0.05).Conclusion:The use of oxytocin,strictly regulate the person responsible for the density and the speed,to achieve effective uterine contrac-tion is the key to success,improve safety induction,and shorten delivery time.