目的探讨西咪替丁联合潘生丁治疗过敏性紫癜的临床疗效。方法将在我院2012年6月至2013年6月收治的过敏性紫癜86例患者,随机分为观察组和对照组,观察组给予西咪替丁联合潘生丁治疗,对照组给予泼尼松、维生素C、维生素D、钙剂、氯雷他定治疗。比较两组患者临床疗效及不良反应的发生情况。结果观察组总有效率93.02%,对照组有效率79.07%,两组总有效率具有差异性(P0.05)。且观察组患者皮肤紫癜消退时间,临床症状消失时间,住院天数均明显低于对照组,两组相比具有差异性(P0.05),西咪替丁联合潘生丁也无明显不良反应。结论西米替西联合潘生丁治疗过敏性紫癜疗效显着,且无严重不良反应,使用便利,患者依从性好,值得临床广泛推广和使用。

Objective The discussion cimetidine and dipyridamole combination to treat the allergic purpura the clinical curative effect. Methods The method the allergic purpura 86 example patients who from June 2012 to June 2013 will admit in my courtyard, will divide into the observation group and the control group stochastically, the observation group gives the cimetidine and dipyridamole combination to treat, the control group will give prednisone, vitamin C, vitamin D, the calcium medicinal preparation, the loratadine. Two groups were compared the clinical efficacy and adverse reactions. Results Finally observation group total effectiveness 93.02%, control group effectiveness 79.07%, two groups of total effectiveness have the difference (P<0.05). Also the observation group patient skin purpura retrogression time, the clinical symptom vanishing time, in hospital number of days obviously is lower than the control group, two groups compare have the difference (P<0.05), the cimetidine and dipyrida

目的观察临床表现,可能病因及加巴喷丁疗效观察。方法选择2008年~2012年以来郑州大学第五附属医院神经内科主诉头盖部圆形区域内疼痛患者共18例,对其头痛的临床特点进行分析,并给予加巴喷丁治疗。结果所有患者均为头部圆形或类圆形区域内疼痛,边界较清楚,头痛部位多位于头顶部。疼痛部位和性质不随时间变化而变化。加巴喷丁治疗硬币性头痛有一定疗效。结论硬币性头痛有其特征性临床表现,加巴喷丁可能有一定治疗作用。

Objective To explore the clinical features , probably pathogenesis of nummular headache and responsive to gabapentin .Methods From 2008 to 2012,18 patients with nummular headache from Depart-ment of Neurology of the Fifth Affiliated Hospital of the Zhengzhou University were selected ,their clinical fea-tures of the headache were analyzed and prescribed gabapentin .Results The headache of all patients present focal and well-circumscribed pain fixed within a round , or elliptical-shaped region of the head .The symptomatic area was located in the parietal .The pain was usually mild to moderate in intensity but may be severe .Gabapen-tin play a role in treating nummular headache .Conclusion Patients with nummular headache have typical clinical features .Gabapentin may play a promising role .

1850年来华的美国长老会传教士丁韪良（William Alexander Parsons Martin）在华62年。伴随着传教士入华和中西文化的相遇，丁韪良的传教活动也须应对中西文化间的冲突和融合问题。国内虽对丁韪良的活动有丰富的研究，但缺乏在跨文化视野下探讨其传教策略的转变。文章拟从跨文化视角，围绕文化冲突、融合的主线来阐释丁韪良不同时段的不同传教策略与相应活动，这对深入认识、理解和客观评价该时期传教士群体在华的活动以及其活动在中西文化交流史上的作用具有重要意义。

As an American Presbyterian missiona ry, William Alexander Parsons Martin came to China in 1850 and stayed in China for 62 years. With the encounter of the Chinese culture and the Western cul-ture, Martin had to deal with the confrontation between these two cultures and integrate different cultural ele-ments in his missionary activities. Although the research on Martin’s activities is diversified at home, it still lacks the analysis on the transformation of his missionary strategies from the cross-cultural perspective. Based on the framework of confrontation, integration between Chinese culture and Western culture, this paper tries to analyze Martin’s missionary activities and strategies in different times from the cross-cultural perspective. The analysis are meaningful to deeply understand the missionary activities in Martin’s age, and objectively evaluate their significance in the history of Sino-Western culture exchange.

目的：旨在探讨奥美拉唑联合法莫替丁治疗反流性食管炎的临床疗效。方法随机将我院从2012年6月-2014年6月期间收诊的114例反流性食管炎患者分为奥美拉唑组、法莫替丁组与联合用药组，通过2个疗程的治疗，观察三组患者的临床疗效与内窥镜复查结果。结果比较三组患者的临床疗效与内窥镜复查结果显示，联合用药组中痊愈的例数与总有效率均较奥美拉唑组与法莫替丁组差异显著（P〈0.05），且奥美拉唑组与法莫替丁组相比亦有统计学差异（P〈0.05）。结论奥美拉唑联合法莫替丁治疗反流性食管炎疗效更切实，其次为奥美拉唑，最后为法莫替丁。

Objective To explore the clinical curative effect on reflux esophagitis of omeprazole combined with famotidine. Meth-ods 114 cases of reflux esophagitis patients selected from June in 2012 to June in 2014 were randomly divided into omeprazole group, famotidine group and the combination group. The clinical efficacy of three groups of patients and the endoscopic check re-sults were observed after the two courses of treatment. Results The clinical efficacy of three groups of patients and endoscopic check results were compared and showed that the cases and the total effective rate of the recovery in the combination group were significant different with the others (P<0.05);and compared with famotidine group, that in the omeprazole group also changed sta-tistically significantly (P<0.05). Conclusion The clinical curative effect on reflux esophagitis of omeprazole combined with famoti-dine was best, followed by omeprazole, and that of famotidine was the last.

探讨改变生活方式对学龄期儿童喉咽反流性疾病(LPRD)的疗效。方法:2013年8月-2014年2月收治学龄期儿童36例,咽喉部临床表现较突出,胃食管反流的症状不典型,咽喉部常规检查所有患者表现为不同程度的咽喉部阳性体征。间接喉镜见所有患者杓间区黏膜充血。随机分为两组,分别给予吗丁啉及吗丁啉联合生活方式指导等治疗2周,分析上述2种方法治疗前后反流、咽喉部症状及体征的改变情况。结果:吗丁啉联合生活方式指导组患者经治疗2周后,总有效率88.9%;吗丁啉组治疗2周后,总有效率55.6%。结论:吗丁啉联合生活方式指导治疗学龄期儿童LPRD的疗效好,可在基层医院推广。

Objective:To explore the effect of the changes of life style on school-age children laryngopharyngeal reflux disease(LPRD).Methods:36 school-age children were selected from August 2013 to February 2014.The throat clinical performance was more prominent,and the gastroesophageal reflux symptoms were not typical.The throat routine examination of all patients showed different degree of laryngopharyngeal signs.Indirect laryngoscope showed all patients interarytenoid region mucosa hyperemia.They were randomly divided into 2 groups,and they were given domperidone and domperidone combined with lifestyle guide for 2 weeks treatment.Then we analyzed the reflux,throat symptoms and signs changes of 2 methods before and after the treatment.Results:After 2 weeks,the total effective rate of domperidone combined with lifestyle guide treatment group was 88.9% ,and the total efficiency of domperidone treatment group was 55.6% .Conclusion:The therapeutic effect of domperidone combined with life