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双语推荐:序贯透析

目的:观察序贯结肠透析对慢性早中期肾功能衰竭的疗效。方法:对300例慢性早中期肾功能衰竭的患者进行序贯结肠透析治疗,观察其症状,治疗前后血肌酐尿素氮水平的变化。结果:300例患者中,总有效率98%,肌酐尿素氮水平有明显变化。结论:序贯结肠透析对慢性早中期肾功能衰竭患者疗效显著。
Objective:To observe the sequential colon dialysis for chronic renal failure in early and mid-efficacy.Methods:300 cases of chronic renal failure in early and mid-sequential colon dialysis patients,the symptoms observed before and after treatment serum creatinine levels in blood urea nitrogen. Results:300 patients,the total efficiency of 98%,creatinine blood urea nitrogen levels change significantly.Conclusion:sequential colon dialysis for chronic renal failure patients early and mid-significant effect.

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目的探讨左旋卡尼汀对维持性血液透析患者治疗中低血压和血C-反应蛋白(CRP)水平的影响。方法将2011年1月至2013年12月收治的32例血液透析治疗中经常发生低血压患者分为四组,每组8例。四组均行标准透析,其中三组在标准透析基础上进行其他透析。标准透析组:行1周标准透析(透析液温度37℃,钠浓度140 mmol/L);高-低钠序贯透析组:透析前3 h透析液钠浓度150 mmol/L,最后1 h降至135 mmol/L;低温透析组:整个透析透析液温度为35.5℃;左旋卡尼汀组:标准透析结束后静脉注射左旋卡尼汀1.0 g,每周2次,共12周。四组共观察12周,比较各组间低血压发生率及血CRP水平。结果 12周后,左旋卡尼汀组低血压发生率[16.0%(40/250)]低于标准透析组[90.0%(225/250)]、低温透析组[20.0%(48/240)]和高-低钠透析组[50.0%(120/240)],差异均有统计学意义(P0.01或0.05)。治疗后左旋卡尼汀组血CRP水平较治疗前降低,差异有统计学意义(P0.05);其他三组血CRP较治疗前无明显变化,差异均无统计学意义(P0.05)。结论左旋卡尼汀能有效减少血液透析中低血压的发生率,同时可降低血CRP水平。
Objective To study the effects of L-carnitine on intradialytic hypotension(IH) and the levels of C-reactive protein(CRP) in maintenance hemodialysis patients. Methods A total of 32 hemodialysis patients with regular IH,who were en-rolled in the hospital from January 2011 to December 2013 ,were selected and divided into four groups after standard hemodialy-sis,8 cases in each group:standard hemodialysis group with 1-week standard hemodialysis (hemodialysis temperature:37 ℃, sodium concentration:140 mmol/L );sequential sodium group with the sodium concentration in dialysate in the first 3 h was 150 mmol/L,then reduced to 135 mmol/L in the last 1 h);low temperature hemodialysis group with the dialysate temperature was 35.5℃in the whole process of hemodialysis;and L-carnitine group with intravenous injection of 1.0 mg L-carnitine after standard hemodialysis,2 times a week for 12 weeks. The occurrence rate of hypertension and serum CRP level among the groups were com-pared after

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目的 探讨血浆置换联合持缓式血液透析滤过治疗重型肝炎的疗效和安全性。方法 选择40例重型肝炎患者序贯应用血浆置换联合持缓式血液透析滤过治疗作为治疗组,40例重型肝炎患者单纯应用血浆置换作为对照组,分别观察两组治疗前后症状、体征变化,比较治疗前后血生化及血氨。结果 两组患者均能完成治疗。两组患者治疗前后各肝功能指标比较差异有统计学意义(P〈0.05),治疗组低血钠改善、近期有效率增高、病死率降低(P〈0.05)。结论 血浆置换联合持缓式血液透析滤过治疗能显著改善重型肝炎患者肝功能,疗效比单纯应用血浆置换治疗提高,是辅助治疗重型肝炎的一种安全有效治疗手段。
Objective To study the efficacy and safety of plasma exchange combined with slow type hemodialysis in the treatment of severe hepatitis. Methods 40 severe hepatitis patients with sequential application of plasma exchange combined with a slow type hemodialysis therapy were selected as the treatment group, 40 severe hepatitis patients with simple application of plasma exchange were selected as the control group. The primary outcome was a composite of the changes of symptoms and signs before and after treatment, blood chemistry and blood ammonia levels before and after treatment. Results Both of the patients in the two groups were able to complete the treatment. The liver function indexes before the treatment were significantly different from those after the treatment (P<0.05). Hyponatremia in the treatment group and recent efficiency improved, while fatality rate reduced (P<0.05). Conclusions Plasma exchange combined with a slow type hemodialysis therapy can significantly improve the liv

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水肿是肾病综合征的主要表现之一,按程度可分为轻、中、重度,其形成机制复杂.关于儿童肾病综合征水肿的治疗,传统方法包括低钠限盐饮食,静脉输注血浆、白蛋白和低分子右旋糖酐,应用利尿剂和利尿合剂等.大部分肾病综合征水肿患儿经过上述治疗后可缓解,但也有部分患儿水钠潴留严重,经常规治疗后往往疗效不佳或复发.这种状态在临床上通常称为难治性(顽固性)水肿.难治性或顽固性水肿一直是儿童肾病综合征治疗的重点和难点,水肿严重者可能合并心力衰竭、肺水肿、低血容量休克甚至急性肾衰竭等危及生命的并发症.近年来有学者提出可考虑应用单纯超滤(isolated ultrafiltration,IUF)、血液透析序贯透析、缓慢连续性超滤(slow continuous ultrafiltration,SCUF)、肾脏持续替代治疗等血液净化技术治疗肾病综合征水肿,且有相关临床研究证实血液净化在肾病综合征严重水肿治疗中有一定疗效.但血液净化技术毕竟为有创的治疗手段,存在并发症及不良反应等风险,故应用前需进行合理的病情评估并严格遵循其适应证.现重点介绍并探讨血液净化在肾病综合征严重水肿中的合理应用及相关的注意事项.
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目的:探讨钠曲线联合低温透析预防透析在血液透析相关性低血压的作用。方法对于我院2012年6月至2013年20例维持性血液透析患者进行先后自身对照,实验组选用钠曲线联合低温透析4周,对照组仅采用低温透析,观察比较两组患者血液透析中低血压、头昏出汗、肌肉痉挛发生率。结果低温透析与低温+钠曲线透析两种模式均能显著降低透析低血压、头晕出汗、肌肉痉挛等透析并发症发生率。(P<0.01)。而低温+钠曲线透析较低温透析降低透析急性并发症效果更显著。(P<0.05)结论单纯低温透析及钠曲线联合低温透析均可减少血液透析低血压发生率,钠曲线联合低温透析防止低血压效果更为明显。
Objective To evaluate the effects of blood volume monitoring combined with dialysate sodium and progressive low temperature on hemodialysis-related hypotension.Method Two groups of 20 patients suffering from uremia with conventional hemodialysis were chosen by the blood pressure during hemodialysis interphase.Group A’s patients received dialysate sodium and progressive low temperature proifle hemodialysis for 4 week. Group B’s patients received low temperature on hemodialysis-related for 4 week. To observe and compare the incidence of the low blood pressure,dizziness,naupathia,disgor ge,muscle spasm.Results Using of dialysate sodium and progressive low temperature can obviously reduce the incidence of the acute eomplications of hemodialysis(P<0.05).Conclusion Using of dialysate sodium and progressive low temperature can obviously reduce the incidence of the acute eomplications of hemodialysis.

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目的:了解腹膜透析患者对腹膜透析相关培训的依从性,探讨患者依从性与腹膜透析相关并发症的关系,为降低腹膜透析的并发症,改善腹膜透析患者的预后性提供参考依据。方法采用自行设计的调查表对60例透析超过半年的腹膜透析患者进行调查,分析患者依从性与腹膜透析相关并发症的关系。结果通过系统的腹膜透析透析前培训,患者能配备透析相关设备,但操作过程存在不规范行为,尤其以年纪大、合并基础疾病患者明显。腹膜透析相关并发症与患者依从性存在负相关关系。结论腹膜透析患者依从性与其并发症的发生有关,提高患者对透析培训的依从性,有助改善患者透析预后。
Objective Investigating on compliance of patients with peritoneal dialysis and assessing relationship with the complication.Methods We surveyed 60 patients who car ied out peritoneal dialysis more than half a year and assessed the relationship between their compliance and the complication during peritoneal dialysis. Results Many people can not achieve Peritoneal dialysis in standard.There is a negative correlation between complications and patient compliance. Conclusion Improving the compliance of patients on dialysis training may improve their prognosis.

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目的:研究不同透析方式对维持性血透患者IL-6、CRP的影响。方法选取90例透析患者,随机分为血液透析( HD)、血液透析滤过( HDF)、血液透析+血液灌流( HDP)组,每组30例。检测透析前及透析2月后血清IL-6及CRP浓度。令选取10名健康体检者作为对照组。结果所有透析患者透析前后IL-6及CRP均显著高于对照组。透析后HDP组IL-6及CRP均显著下降,且均低于HD及HDF组。结论血液透析联合血液灌流能够改善透析患者微炎症状态。
Objective To study the IL-6 and CRP level of maintenance hemodialysis patients using different hemodialysis methods. Methods 90 cases of dialysis patients were randomly divided into hemodialysis ( HD) , hemodiafiltration( HDF) , hemodialysis+hemoperfusion( HDP) group, 30 cases in each group. Serum IL-6 and CRP level were mesured before and 2 months after hemodialysis. 10 healthy subjects were selected as con-trols. Results All dialysis patients IL-6 and CRP level were significantly higher than control group. After dialysis, HDP group IL-6 and CRP were significantly decreased, and were lower than the HD and HDF groups. Conclusion Hemodialysis and hemoperfusion can improve micro-inflammatory state in dialysis patients.

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目的:观察采用低温联合可调钠及超滤曲线透析模式对透析中低血压的治疗效果。方法:2012年-2013年,将42例低血压患者分别采用常规透析及联合模式透析(低温联合可调钠及超滤曲线),每组患者连续治疗15次,观察每次透析前、透析中每小时、下机15分钟后的血压变化。结果:采用常规透析模式的患者透析中血压下降明显(P〈0.05),而采用联合透析模式的患者透析中血压变化较小(P〉0.05)。结论:采用低温联合可调钠及超滤曲线技术可预防透析中低血压,保证透析治疗的顺利进行。
Objective To Observate the ef ect on hypotension by using low-temperature joint adjustable sodium and ultrafiltration profile in dialysis treatment.Methods During 2012 ~2013,42 patients with hypotension were respectively by conventional dialysis and joint mode dialysis (low temperature joint adjustable sodium and ultrafiltration profile),each group of consecu-tive patients treated for 15 times,then observe the changes of blood pressure before dialysis,during dialysis per hour ,15 minutes after dialysis.Result Blood pressure of dialysis patients using conventional dialysis mode indecreased significantly (P 0.05).Conclusions Low-temperature joint adjustable sodium and ultrafiltration profile technology can prevent intradialytic hypotension,guarantee the smooth progress of the treatment of hemodialysis.

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目的探讨集束化护理干预在维持性血液透析中的应用效果。方法选择陕西省友谊医院2012年1月~2013年1月进行维持性血液透析患者100例临床资料,依据护理措施不同分为常规护理组50例和集束化护理组50例。观察两组维持性血液透析患者血液透析依从性、生活习惯依从性、饮食依从性和运动依从性情况,观察两组维持性血液透析患者透析前血压、透析过程中血压、透析前血钠浓度、透析后血钠浓度、透析前体温、透析过程中体温情况。结果两组患者透析前血压、透析前血钠浓度、透析后血钠浓度、透析前体温差异无统计学意义(P0.05);集束化护理组血液透析依从性、生活习惯依从性、饮食依从性和运动依从性均高于常规护理组,集束化护理组透析过程中血压、透析过程中体温均优于常规护理组,差异均有统计学意义(P0.05)。结论集束化护理干预在维持性血液透析中的应用后可以明显提高患者治疗依从性,减少不良反应发生,值得临床推广应用。
Objective To investigate application result detection of hemodialysis by cluster nursing intervention. Meth-ods 100 cases of hemodialysis patients in Shaanxi Friendship Hospital from January 2012 to January 2013 were select-ed and divided into conventional nursing group with 50 cases and cluster based nursing group with 50 cases. The hemodialysis compliance, living habits compliance, dietary compliance, exercise adherence of two groups were detected, the blood pressure before dialysis, blood pressure during dialysis, serum sodium concentration before dialysis, serum sodium concentrations after dialysis, body temperature before dialysis, temperature in the process of dialysis of two groups were detected. Results The differences of blood pressure before dialysis, serum sodium concentration before dialysis, serum sodium concentrations after dialysis, body temperature before dialysis of two groups were not statistical-ly significant (P> 0.05). Hemodialysis compliance, living habits complia

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目的:观察低钙血液透析滤过对慢性肾衰竭维持性血液透析患者顽固性高血压病的疗效。方法选择62例维持性血液透析伴顽固性高血压病患者,随机分为对照组、血液透析滤过组、低钙血液透析滤过组。在相同治疗方案的基础上,对照组行常规血液透析治疗,血液透析滤过组改行血液透析滤过治疗,低钙血液透析滤过组除改血液透析滤过外,换用1.25 mmol/L 低钙透析液,疗程为12周。结果治疗12周后,血液透析滤过组和低钙血液透析滤过组的血压、β2微球蛋白、血浆肾素、血管紧张素均比治疗前明显下降(P 均<0.05),低钙血液透析滤过组血压下降更为明显(P 均<0.05)。血液透析滤过组和低钙血液透析滤过组头晕、头痛及胸闷、气促发生率均低于对照组(P 均<0.05)。结论血液透析滤过能有效治疗维持性血液透析患者顽固性高血压病,加用低钙透析液效果更佳。
Objective To investigate the clinical efficacy of hemodiafiltration with low-calcium dialy-sate in treatment of refractory hypertension in hemodialysis patients.Methods Sixty-two hemodialysis patients with refractory hypertension were chosen and randomly divided into the control group,hemodiafiltration group and hemodiafiltration with low-calcium dialysate group.Based upon the basic treatment,patients in the hemo-diafiltration group received hemodiafiltration and their counterparts in the hemodiafiltration with low-calcium di-alysate group were subjected to both hemodiafiltration with 1 .25 mmol/L calcium dialysate.The course of treat-ment endured for 1 2 weeks.Results Following 1 2-week therapy,the blood pressure,β2-microglobulin,plas-ma rennin and angiotensin in the hemodiafiltration and hemodiafiltration with low-calcium dialysate groups were significantly decreased (all P <0.05),especially the more significant decrease in blood pressure of patients receiving hemodiafiltr

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